CRITICAL LIMB ISCHEMIA TREATMENT MARKET SIZE AND SHARE ANALYSIS - GROWTH TRENDS AND FORECASTS (2024-2031)

Critical Limb Ischemia Treatment Market Size and Trends

The global critical limb ischemia treatment market is estimated to be valued at USD 5.10 Bn in 2024 and is expected to reach USD 9.11 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 8.6% from 2024 to 2031.

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The critical limb ischemia treatment market is expected to witness prominent growth over the forecast period. The rising geriatric population worldwide and the growing prevalence of peripheral artery disease are major factors contributing to the increased demand for critical limb ischemia treatment. Furthermore, the increasing adoption of minimally invasive surgeries and the growing number of regulatory approvals for advanced treatment options are expected to provide new opportunities for players in the market. However, the high cost of treatment and lack of reimbursement policies in developing nations may hinder the market growth.

Rising Prevalence of Diabetes

 The global prevalence of diabetes has been steadily increasing over the past few decades. According to estimates, over 460 million adults were living with diabetes in 2019, compared to around 108 million in 1980. Type 2 diabetes in particular has risen dramatically worldwide due to increasing levels of obesity and sedentary lifestyles. Diabetes greatly elevates the risk of developing peripheral artery disease and critical limb ischemia, as high blood sugar levels can damage and narrow the arteries supplying blood to the legs and feet over time. It is projected that by 2030, diabetes will affect over 700 million people globally if preventive measures are not taken. As more people are afflicted by this chronic condition, cases of CLI Critical Limb Ischemia are also expected to grow substantially. Early treatment of diabetes and maintaining optimal blood sugar control can help reduce complications, but many patients may still develop PAD and require CLI Critical Limb Ischemia treatment. The growing diabetes epidemic worldwide will therefore act as a key driver for the critical limb ischemia market in the coming years. The increasing prevalence of diabetes poses a heightened risk for patients developing chronic limb-threatening ischemia (CLTI) due to peripheral arterial disease. For instance, with diabetes rates projected to rise, as indicated by the International Diabetes Federation's 2022 statistics, from 32 million in the U.S. to 36 million by 2050, there is a growing concern over the potential damage caused by high blood sugar levels to nerves regulating heart and blood vessel functions. This scenario is anticipated to drive the demand for more effective treatments, thereby stimulating the market growth in arterial disease management.

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Growing Number of Smokers

The growing number of smokers around the world is having a significant impact on the critical limb ischemia treatment market. As smoking is one of the major risk factors that can lead to peripheral artery disease (PAD) and critical limb ischemia, the rising prevalence of smoking will fuel the need for effective treatment options for this condition. PAD occurs when arteries in the legs or arms become narrowed due to buildup of fat, cholesterol, calcium or other substances over many years of smoking. Smoking constricts the blood vessels and reduces blood flow to arms and legs. It damages the inner lining of arteries and promotes formation of blood clots. All of these smoking-related effects increase the chances of developing critical limb ischemia, which is the most severe form of PAD that occurs when limbs do not receive adequate blood flow. According to recent data from the World Health Organization, In July 2023 approx one in five adults smoke tobacco on a daily basis globally. While smoking rates are declining in high-income countries, they are still elevated and rising in many low and middle-income countries. Every year over 8 million people die due to tobacco use. If current trends continue, tobacco is expected to kill more than 1 billion people globally in the 21st century. The growth in the overall number of smokers indicates that more people will develop critical limb ischemia due to PAD in the coming years due to prolonged smoking.