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Growing Number of Smokers
The growing number of smokers around the world is having a significant impact on the critical limb ischemia treatment market. As smoking is one of the major risk factors that can lead to peripheral artery disease (PAD) and critical limb ischemia, the rising prevalence of smoking will fuel the need for effective treatment options for this condition. PAD occurs when arteries in the legs or arms become narrowed due to buildup of fat, cholesterol, calcium or other substances over many years of smoking. Smoking constricts the blood vessels and reduces blood flow to arms and legs. It damages the inner lining of arteries and promotes formation of blood clots. All of these smoking-related effects increase the chances of developing critical limb ischemia, which is the most severe form of PAD that occurs when limbs do not receive adequate blood flow. According to recent data from the World Health Organization, In July 2023 approx one in five adults smoke tobacco on a daily basis globally. While smoking rates are declining in high-income countries, they are still elevated and rising in many low and middle-income countries. Every year over 8 million people die due to tobacco use. If current trends continue, tobacco is expected to kill more than 1 billion people globally in the 21st century. The growth in the overall number of smokers indicates that more people will develop critical limb ischemia due to PAD in the coming years due to prolonged smoking.
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