Cancer vaccines manufacturers are concentrating on producing novel vaccinations to treat various malignancies. They are expected to obtain a competitive advantage in the market and expand their market share as a result of this. For example, in November 2019, NEC Corporation and VAXIMM AG announced a collaboration to research innovative neoantigen cancer vaccines. In July 2019, Boehringer Ingelheim International GmbH announced the purchase of AMAL Therapeutics SA, a firm focusing on cancer drug development cancer vaccines by its KISIMA technology. The acquisition is intended to strengthen Boehringer's cancer portfolio and platform. The rising frequency and incidence of various malignancies is likely to boost the growth of the Cancer Vaccines Market.
Market Players in the Cancer Vaccine Industry:
1. AstraZeneca
AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacturing, and commercialization of prescription medicines. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom. The company serves primary care and specialty care physicians through distributors and local representative offices in the United Kingdom, rest of Europe, the Americas, Asia, Africa, and Australasia. It has a collaboration agreement with Regeneron Pharmaceuticals, Inc. to research, develop, and commercialize small molecule medicines for obesity; Neurimmune AG to develop and commercialize NI006; Ionis Pharmaceuticals, Inc. to develop eplontersen, a liver-targeted antisense therapy in Phase III development for the treatment of transthyretin amyloidosis; Proteros Biostructures GmbH to jointly discover novel small molecules for the treatment of hematological cancers; Sierra Oncology, Inc. to develop and commercialize AZD5153. In June 2020, AstraZeneca announced its collaboration with Accent Therapeutics to discover, develop, and commercialize transformative therapeutics targeting RNA-modifying proteins for the treatment of cancer.
2. Astellas Pharma Inc
Astellas Pharma is a pharmaceutical company conducting business in more than 70 countries around the world. Founded in April, 2005, headquartered in Tokyo, Japan. In February 2020, Astellas Pharma Inc. and Seattle Genetics Inc. announced that the U.S. FDA has granted Breakthrough Therapy designation for PADCEV, in combination with immune therapy pembrolizumab in First-line advanced bladder cancer.
3. Merck & Co. Inc.
Merck & Co., Inc. operates as a healthcare company worldwide. It operates through two segments, Pharmaceutical and Animal Health. Merck & Co., Inc. was founded in 1891 and is headquartered in Kenilworth, New Jersey.
4. GlaxoSmithKline plc
GSK plc, together with its subsidiaries, engages in the creation, discovery, development, manufacture, and marketing of pharmaceutical products, vaccines, over-the-counter medicines, and health-related consumer products. GSK plc was founded in 1715 and is headquartered in Brentford, the United Kingdom. GSK plc and Wave Life Sciences Ltd in December, 2022 announced a strategic collaboration to advance oligonucleotide therapeutics, including Wave’s preclinical RNA editing programme targeting alpha-1 antitrypsin deficiency (AATD), WVE-006.
5. Pfizer Inc.
Pfizer Inc. was founded in 1849 and is headquartered in New York, New York. Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sell biopharmaceutical products worldwide. In December, 2022 announced the U.S. Food and Drug Administration (FDA) granted Emergency Use Authorization (EUA) of their Omicron BA.4/BA.5-adapted bivalent COVID-19 vaccine as the third 3-µg dose in the three-dose primary series for children 6 months through 4 years of age. for the field of oncology such as Trastuzumab deruxtecan, Anti-HER3-ADC, Quizartinib, Milademetan, Valemetostat, Pexidartinib, Edoxaban, Prasugel, and Microgabalin. The company was founded on September 28, 2005 and is headquartered in Tokyo, Japan
6. Serum Institute of India Pvt. Ltd.
Serum Institute of India Pvt, Ltd. is the world's largest vaccine manufacturer by number of doses produced and sold globally (more than 1.5 billion doses), supplying the world's least expensive and WHO-accredited vaccines to as many as 170 countries. It was founded in 1966, headquartered in Pune, India. On March 23, 2022 Novavax, Inc. and Serum Institute of India Pvt. Ltd. announced that the Drugs Controller General of India (DCGI) has granted emergency use authorization (EUA) for Novavax' protein-based COVID-19 vaccine for adolescents aged ≥12 to <18 years in India. The vaccine, also known as NVX-CoV2373, is manufactured and marketed in India by SII under the brand name Covovax™ and is the first protein-based vaccine authorized for use in this age group in India.
7. CSL Limited
CSL Limited researches, develops, manufactures, markets, and distributes biopharmaceutical and allied products in Australia, the United States, Germany, the United Kingdom, Switzerland, China, and internationally. The company operates through two segments, CSL Behring and CSL Seqirus. CSL Limited was founded in 1916 and is headquartered in Parkville, Australia. On Oct. 5, 2022 CSL announced results from the preclinical studies of the company's self-amplifying messenger RNA (sa-mRNA) influenza vaccine candidates, the next generation of mRNA vaccines. The data, published in Molecular Therapy – Methods and Clinical Development, indicate that the sa-mRNA influenza vaccine candidates produced a potent, cross-reactive immune response against pandemic and seasonal influenza strains, A(H5N1) and A(H1N1).1
8. Sanofi S.A.
Sanofi, together with its subsidiaries, engages in the research, development, manufacture, and marketing of therapeutic solutions and was founded in 1973. The company is headquartered in Paris, France and is operational in 100 plus countries. Sanofi and Innate Pharma SA announced in December, 2022 an expansion of their collaboration, with Sanofi licensing a natural killer (NK) cell engager program targeting B7H3 from Innate’s ANKET (Antibody-based NK Cell Engager Therapeutics) platform.
*Definition- Cancer is the world's second largest cause of illness and mortality. Cancer is caused primarily by gene mutation and less rarely by inherited genes. It is classified as carcinomas, lymphomas, leukaemias, brain tumours, and sarcomas based on the kind of cell that begins to develop malignant.
