Glucagon-like peptide-1 (GLP-1) receptor agonists bind to GLP-1 receptors and activate it to stimulate physiological processes in the body. GLP-1 receptor agonists interact with GLP-1 receptor present in the pancreatic beta cells to stimulate insulin secretion. Thus, GLP-1 receptor agonists can be used for treatment of diabetes. Glucagon is a hormone responsible for increasing the concentration of glucose in the blood by stimulating the liver to convert glycogen into glucose.
In 2021, the global GLP-1 Receptor Agonist Market is estimated to be valued at US$ 12,720.6 Million and is expected to exhibit a CAGR of 6.1% during the years (2021-2028)
Key Leaders in the Glp 1 Receptor Agonist Industry:
1) Pfizer Inc.
Pfizer Inc. is a pharmaceutical and biotechnology company based in America. It was founded in the year 1849. Pfizer manufactures and produces vaccines and medicine related to oncology, neurology, cardiology, and immunology. The corporation has produced various products that yield more than US$1 billion in annual revenue.
The company ranked 64th on the Fortune 500 and 49th on the Forbes Global 2000. The headquarters are located in New York City, U.S. and the products manufactured are sold worldwide. The company was founded by Charles Pfizer and Charles F. Erhart.
As of January 2023, Pfizer Inc. and Abzena have entered into an agreement under which Pfizer will be acquiring Abzena’s manufacturing facility in Sanford, North Carolina.
2) Sanofi S.A.
Sanofi S.A. is a multinational pharmaceutical company that engages in the research and development, of pharmacological products, in the prescription market. The firm cover therapeutic areas like Cardiovascular, central nervous system, diabetes, internal medicine. The company was founded in 973 and the headquarters are located in Paris, France. Products manufactured include Medications, Genetic drugs, Vaccines, Animal Health, etc.
In December, 2022 Sanofi expanded its collaboration with Innate Pharma, with Sanofi licensing a natural killer (NK) cell nagger program targeting B7H3 from Innate’s ANKET platform.
3) GlaxoSmithKline GSK plc.
GSK Plc. Is a British Multinational pharmaceutical and biotechnology company founded in the year 2000. The headquarters are located in London, England, UK. GlaxoSmithKline is the tenth largest pharmaceutical company and has ranked 294th on the 2002 Fortune Globes 500. The company was founded by Joseph Nathan. The company manufacture products for major diseases like asthma, cancer, infections and mental health.
In April 2022, the company announced its plans of acquiring Sierra Oncology Inc. for U.S$ 1.9 Billion. In May 2022, GSK announced it would acquire Affinivax and its phase II 24- Valent pneumococcal vaccine candidate for up to $3.3 Billion.
4) AstraZeneca Plc.
AstraZeneca Plc. Is a multinational pharmaceutical and biotechnology company. The company is known for manufacturing products for major diseases like Oncology, Cardiovascular, Infection, Respiratory and Inflammation. Apart from that, it has also been a part of developing the Oxford-AstraZeneca Covid-19 vaccine. The company was founded in 1999 and the headquarters are located in Cambridge, England, UK.
In July of 2021 AstraZeneca completed the acquisition of Alexion Pharmaceuticals, Inc. In January of 2023, AstraZeneca also announced its plans to acquired CinCor a biopharmaceutical company based in the U.S.
5) Amgen Inc.
Amgen Inc. (Applied Molecular Genetics Inc.) is a biopharmaceutical company based in America. It is one of the world’s largest biotechnology company. The company was founded in the year 1980 on the 8th of April. The headquarters are located in Thousand Oaks, California, U.S. The company sells its products worldwide and some of them include Aimovig, Enbrel, Prolia, Xgeva, Nplate etc. The company was founded by William K.
In August 2022, Amgen agreed to acquire ChemoCentryx, a company that makes Tavneos, a drug treatment for rare diseases. Amgen acquired the company for US$ 3.7 Billion.
6) Sun Pharmaceutical Industries Limited
Sun Pharma is an Indian multinational pharmaceutical company. Sun Pharma is the largest pharmaceutical company in India and the fourth largest specialty generic pharmaceutical company in the world. Sun Pharma was founded in the year 1983, and the headquarters are located in Mumbai, India. The company was founded by Dilip Shanghvi.
In January 2023, Sun Pharma completed the acquisition of Concert Pharmaceuticals, a developer of innovative medicine for patients with chronic diseases. For US$ 576 Million.
