Scaffolds are made of materials that encourage the growth of cells or tissues in a way that encourages the development of new, therapeutically valuable tissues. These scaffolds can support damaged organs or organ systems. Customized scaffolds for a particular injured organ or organ system can be made with the help of tissue engineering and regenerative medicine. Tissue engineering is a part of biomedical engineering. To retain, repair, or improve living tissues, it makes use of cells, the proper biochemical and physiochemical components, and sophisticated engineering procedures. To create new tissue and encourage healing, scaffolds can be positioned directly at the site of an injury or created in a lab. Biodegradable scaffolds breakdown quickly after implantation to allow wounded tissue or organ remodeling. Biodegradable scaffolds are produced from natural and synthetic polymers, ceramics, and bioglasses. Hyaluronic acid, CMC, and chitosan are biodegradable scaffold polymers. Synthetic polymers including poly-alpha-hydroxy acids, polycaprolactone, and polyanhydrides degrade quickly.
Tissue engineering and regenerative medicine research to create novel scaffolds for tissue remodeling drives the worldwide biodegradable scaffold market. New products will boost the worldwide biodegradable scaffold market in the next years. As industry participants work harder to gain regulatory clearances, the worldwide biodegradable scaffolds market is likely to develop during the forecast period. Tissue engineering and regenerative medicine research to create novel scaffolds for tissue remodeling drives the worldwide biodegradable scaffold market. New products will boost the worldwide biodegradable scaffold market in the next years. As industry participants work harder to gain regulatory clearances, the worldwide Biodegradable Scaffolds Market is likely to develop during the forecast period.
Leading Companies in the Biodegradable Scaffold Industry:
1. Merck KGaA
Merck KGaA is a German multinational science and technology company, was founded in 1668 and headquartered in Darmstadt, Germany. It operates in 66 countries. In October 2021, Merck opened a second plant in Carlsbad, California, greatly increasing its global CDMO footprint.
2. 3D Biotek LLC
3D Biotek LLC is a biotechnology company, was founded in 2007 and headquartered in New Jersey, United States .It operates globally.
3. Medtronic
Medtronic is an American medical device company, was founded in 1949 and headquartered in Minnesota, U.S. .It operates in more than 150 countries
4. Xanofi
Xanofi is a French multinational pharmaceutical and healthcare company was founded in 1973 and headquartered in Paris, France. It operates in 36 countries.
5. Akron Biotech
Akron Biotech is an innovative biotechnology company focused on manufacturing high quality products for advanced therapies. It was founded in 2006 and headquartered in Florida, United States. It operates in many countries. In April 2022, Akron Bio introduces plasmid DNA plant to reduce regenerative medicine constraints.
6. Nanofiber Solutions
Nanofiber Solutions was founded in 2009 and headquartered in United States. It operates worldwide.
7. Vericel Corporation
Vericel Corporation is a public, American biopharmaceutical company which was known prior to October 2014 as Aastrom Bio. It was founded in 1989 and headquartered in Massachusetts, United States. It operates in United States. In Feb 2022, Vericel announces plans for a brand-new, cutting-edge cell therapy manufacturing facility to support future growth.
8. NuVasive, Inc.
NuVasive, Inc. was founded in 1997 and headquartered in San Diego, California. It operates in over 25 locations around the world. In June 2018, NuVasive, Inc., the leader in spine technology innovation, is working to change spine surgery with minimally disruptive, procedure-integrated solutions. They announced the U.S. launch of AttraX® Scaffold, an absorbable ceramic-collagen bone graft with an optimized surface that has been shown in preclinical testing to lead to more bone formation and faster fusion than traditional ceramic bone grafts.
9. Organogenesis, Inc.
Organogenesis, Inc. was founded in 1985 and headquartered in Massachusetts, United States, The international office is located in Reinach, Switzerland. All products are proudly made in the United States. In Dec 2018, Organogenesis Holdings Inc., a leading regenerative medicine company, completed its previously announced business combination with Avista Healthcare Public Acquisition Corp. ("AHPAC").
10. Biostage, Inc.
Biostage, Inc. was founded in 2012 and headquartered in Massachusetts, United States. It operates in many different countries. In Dec 2022, IQVIA, a top global provider of advanced analytics, technology solutions, and clinical research services to the life sciences industry, has been chosen by Biostage, Inc. as the contract research organization (CRO) to manage its first clinical trial. Biostage, Inc. is a clinical-stage biotechnology company creating regenerative-medicine remedies for disorders of the gastro-intestinal system and the airway resulting from cancer, trauma, or birth defects.
11. In2Bones Global
In2Bones Global was founded in and headquartered in .It operates in .
*Definition: Biodegradable scaffolds are generally considered as indispensable elements for engineering living tissues as they are used as temporary templates with specific mechanical and biological properties similar to native extracellular matrix (ECM).
