Sirolimus, also known as rapamycin, is a strong immunosuppressant that weakens the immune system to help prevent organ rejection after transplant. It also has antifungal and antineoplastic properties and is used to coat coronary stents, prevent organ rejection in renal transplant patients, and treat a lung disease called Lymphangioleiomyomatosis.
Approvals of generic versions of Rapamune for preventing organ transplant rejection are expected to drive the growth of the global Sirolimus Market. The increasing incidence of kidney diseases and related disorders has led to a rise in the number of kidney transplants, which is expected to further drive demand for sirolimus. Major market players are also engaged in research and development activities to introduce optimized dosage forms, which is expected to support market growth over the forecast period. The rising incidence of various syndromes and disorders is also expected to result in increased demand for transplants.
Prominent Companies in the Sirolimus Industry:
- Pfizer Inc.
Pfizer Inc. was established in 1849 and is headquartered in New York, United States. It operates in 181 countries and is engaged in various industries, including biotechnology, healthcare, medical, and pharmaceuticals. In 2023, Pfizer announced that Pfizer’s Sirolimus is under clinical development and currently in Phase II for Amyotrophic Lateral Sclerosis.
- Zydus Cadila Healthcare Ltd., Inc.
Zydus Cadila Healthcare Ltd., Inc., was established in 1952 and is headquartered in Ahmedabad, Gujarat, India. It operates in 50 countries and is engaged in developing and manufacturing an extensive range of pharmaceuticals as well as diagnostics, herbal products, skincare products, and other OTC products. In 2023, Zydus Ltd. received final approval from the United States Food and Drug Administration (USFDA) for sirolimus.
- Actiza
Actiza was established in 2010 and is headquartered in Surat, Gujarat, India. It operates in almost 30 countries and is engaged in various industries, including healthcare and pharmaceuticals.
- Greenstone LLC
Greenstone LLC was established in 1993 and is headquartered in Peapack, New Jersey, United States. It operates in more than 100 countries and is engaged in various industries, including biotechnology and pharmaceuticals.
- Biocon
Biocon was established in 1978 and is headquartered in Bangalore, Karnataka, India. It operates in more than 120 countries and is engaged in various industries, including biopharma, biotechnology, healthcare, and medical.
- Livzon NNR
Livzon NNR was established in 1990 and is headquartered in Qingyuan, Guangdong, China. It engaged in research and development, production, and sales of pharmaceutical products.
- Intas Pharmaceuticals Ltd.
Intas Pharmaceuticals Ltd. was established in 1977 and is headquartered in Ahmedabad, Gujarat, India. It operates in more than 85 countries and is engaged in various industries, including healthcare, manufacturing, and pharmaceuticals.
Definition: Sirolimus is an immunosuppressive medication used to prevent organ rejection in transplant patients and treat certain cancers.
