The prevalence of adult male hypogonadism is expected to increase demand for testosterone replacement therapy. In middle-aged males, the frequency of hypogonadism ranges from 2.1% to 12.8%, according to a 2016 report by the European Association of Urology. In Europe, symptoms of hypogonadism and low testosterone affect 2.1% to 5.7% of males between the ages of 40 and 79. Hypogonadism is more prevalent in older males, obese men, men with co-morbid illnesses, and men with poor health. Furthermore, according to the Therapeutic Advances of Urology Journal: 2016, testosterone rose to become one of the most widely prescribed medications in the United States in 2011. The prevalence of hypogonadism in T2DM patients was found to be 20.7%, according to a study published in the Indian Journal of Endocrinology and Metabolism in 2017. The study evaluated the testosterone insufficiency in 900 males with type II diabetes mellitus (T2DM). Additionally, a moderate percentage of T2DM patients had hypogonadism, with the majority of these individuals falling into the 50–59 year age range.
In 2021, the market for Testosterone Replacement Therapy was estimated to be worth USD 1.98 billion.
Prominent Companies of Testosterone Replacement Therapy Industry:
1. AbbVie, Inc.: Pharmaceutical business AbbVie has a significant presence in oncology and immunology. Humira, the company's best-selling medication, accounts for about half of its current earnings. Early in 2013, the company was separated from Abbott. Allergan's latest acquisition has included a number of new cosmetic and women's health medications. Created in 2012. American headquarters in North Chicago.
2. Bayer AG: A healthcare and agricultural conglomerate from Germany is called Bayer. Health care, which includes pharmaceutical medications, vitamins, and other consumer healthcare products, accounts for about half of the business's sales. With the addition of Monsanto, the company's crop science division, which already comprises seeds, insecticides, herbicides, and fungicides, has grown. Built in 1863. German headquarters are in Leverkusen. A business that specialises in external innovation drug research and development called Evotec and Bayer have been working together since 2012.
3. Endo Pharmaceuticals, Inc.: Founded in 1935. Dublin, Ireland is the location. A specialty pharmaceutical firm called Endo International PLC has a significant presence in a number of medical specialties, including bariatrics, urology, orthopaedics, and endocrinology. Its four business segments are International Pharmaceuticals, Branded Pharmaceuticals, Sterile Injectables, and Generic Pharmaceuticals.
4. Eli Lilly and Company: Eli Lilly is a pharmaceutical company that specialises in immunology, oncology, neuroscience, and endocrinology. Built in 1875. United States headquarters in Indianapolis. Lilly and Entos Pharmaceuticals have signed a research and collaboration agreement to support the creation of novel treatments for a variety of neurologic conditions.
5. Kyowa Kirin International plc: A company that sells prescription drugs for the treatment of unmet medical needs. The business creates prescription drugs with a therapeutic focus on conditions affecting women's health, men who are ageing, and bone ailments. Built in 1995. Scottish headquarters in the United Kingdom. In 2021, Kyowa Kirin and Harvard University signed a strategic research alliance.
6. Pfizer, Inc.: One of the biggest pharmaceutical companies in the world, Pfizer generates close to $50 billion in revenue annually. The company used to sell a wide variety of chemicals and healthcare items, but today the majority of its sales come from prescription medications and vaccinations. Built in 1848. American headquarters in New York. Pfizer and BioNTech Announce Additional Information About Their Partnership to Hasten Global COVID-19 Vaccine Development.
*Definition: The signs and symptoms of low testosterone in men can be improved with testosterone replacement treatment, which comes in the form of injections, pellets, patches, or gels.
