During the course of the projection period, key players are anticipated to increase their research and development efforts in order to develop and introduce tacrolimus. For instance, the biopharmaceutical company VIVUS, Inc. reported encouraging early findings from a Phase 1 clinical research assessing the pharmacokinetic (PK) profile of its VI-0106 in healthy volunteers in June 2018. For the treatment of pulmonary arterial hypertension (PAH), a degenerative condition that makes it difficult for the heart to pump blood through the lungs to be oxygenated and may eventually result in heart failure, VIVUS is developing VI-0106, a patented soft capsule formulation of tacrolimus.
The global Tacrolimus Market is estimated to be valued at US$ 6,485.3 million in 2022 and is expected to exhibit a CAGR of 4.7% during the forecast period (2022-2030).
Prominent Companies in the Tacrolimus Industry:
1. Novartis AG
Novartis AG researches, develops, manufactures, and markets healthcare products in Switzerland and internationally. The company operates through two segments: Innovative Medicines and Sandoz. Novartis AG was incorporated in 1996 and is headquartered in Basel, Switzerland. Novartis AG has a license and collaboration agreement with Alnylam Pharmaceuticals to develop, manufacture, and commercialize inclisiran, a therapy to reduce LDL cholesterol.
2. Astellas Pharma Inc.
Astellas Pharma Inc. was established in the yesr 2005.Its headquarter is located in Northbook, IL. Astellas supported recommendations of Task Force on Climate-related financial Disclosur in 2020.
3. Dr. Reddy's Laboratories
Dr. Reddy's Laboratories Limited, together with its subsidiaries, operates as an integrated pharmaceutical company worldwide. It operates through Global Generics, Pharmaceutical Services and Active Ingredients (PSAI), Proprietary Products, and others segments. Dr. Reddy's Laboratories Limited was incorporated in 1984 and is headquartered in Hyderabad, India. Dr. Reddy's Laboratories Limited was incorporated in 1984 and is headquartered in Hyderabad, India. On Feb 2021, Dr. Reddy’s Laboratories has introduced an orally disintegrating formulation of lansoprazole to the U.S. market. Lansoprazole is a proton pump inhibitor, a mechanism of action designed to reduce the amount of acid made in the stomach and thereby treat conditions including indigestion, heartburn, acid reflux and gastroesophageal reflux disease.
4. Pfizer Inc.
Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products worldwide. Pfizer Inc. was founded in 1849 and is headquartered in New York, New York. The company has collaboration agreements with Bristol-Myers Squibb Company; Astellas Pharma US, Inc.; Myovant Sciences Ltd.; Akcea Therapeutics, Inc; Merck KGaA; Valneva SE; BioNTech SE; and Arvinas, Inc. on December 2022, Pfizer Presents Updated Favorable Elranatamab Data from Pivotal Phase 2 MagnetisMM-3 Trial, early and deep responses, and a manageable safety profile for elranatamab in heavily pretreated patients with advanced multiple myeloma
5. Abbott
Abbott is a global healthcare leader in medical products and devices manufacturing. It serves people in more than 160 countries. Abbott was established in 1888. Abbott launched its Navitor its latest generation transcatheter aortic valve implantation (TAVI) system to treat Aortic Stenosis in India.
6. Glenmark Pharmaceuticals Ltd.
Glenmark Pharmaceuticals Limited, together with its subsidiaries, develops, manufactures, and markets pharmaceutical products. The company was incorporated in 1977 and is based in Mumbai, India. In January, 2023 Glenmark Pharmaceuticals Inc., USA (Glenmark) is pleased to announce it has launched Bumetanide Injection USP, 1 mg/4 mL (0.25 mg/mL) SingleDose Vials and 2.5 mg/10 mL (0.25 mg/mL) Multi-Dose Vials, the generic version of Bumex®1 Injection, 0.25 mg/mL, of Validus Pharmaceuticals LLC.
7. Lupin
Lupin Limited was founded in 1968 and is headquartered in Mumbai, India. Lupin Limited, a pharmaceutical company, develops, produces, markets, and sells a range of branded and generic formulations, biotechnology products, and active pharmaceutical ingredients (APIs). The company is operational in more than 100 countries.
More than 100 countries. Lupin Limited (Lupin) in the month of December, 2022 announced the launch of authorized generic version of PENNSAID® (Diclofenac Sodium Topical Solution), 2% w/w of Horizon Pharma Therapeutics in the United States.
8. Vibcare Pharma Pvt. Ltd.
Vibcare Pharma Pvt Ltd is a growing PCD Pharma company in India and is committed to increase access to high-quality healthcare by developing, producing and marketing affordable pharmaceutical products. It was incorporated in 2013 and has headquarters situated in Chandigarh, India.
*Definition- Tacrolimus is used in conjunction with other medications to treat kidney transplant recipients who are at risk of rejection, which occurs when the immune system of the recipient attacks the donated organ.
