The mission of the Medicines for Malaria Venture (MMV), a non-profit public-private collaboration founded in 1999, is to lessen the impact of malaria in nations where the disease is endemic by creating new treatment alternatives. The development of novel drug entities for the treatment of malaria has been a focus of collaboration between MMV and several of the major pharmaceutical companies. For instance, in December 2019, Ipca Laboratories and Medicines for Malaria Venture collaborated to create Atoguanil, a novel antimalarial co-formulation that combines atovaquone and proguanil. The market for anti-malaria medications worldwide is also expanding dramatically as a result of increased financing from regional governments.
The global Anti-Malarial Drugs Market was valued at US$ 839.1 million in 2019 and is expected to exhibit a CAGR of 4.4% during the forecast period (2019–2027).
Leading Companies in the Anti-Malarial Drugs Industry:
1. Zydus Cadila
Zydus Lifesciences Limited engages in the research, development, production, marketing, distribution, and sale of pharmaceutical. Zydus Lifesciences Limited was founded in 1952 and is based in Ahmedabad, India.
2. Merck KGaA
Merck & Co., Inc. operates as a healthcare company worldwide. It operates through two segments, Pharmaceutical and Animal Health. Merck & Co., Inc. was founded in 1891 and is headquartered in Kenilworth, New Jersey. In January, 2023 Merck completes acquisition of the chemical business of Mecaro.
3. Pfizer Inc.
Pfizer Inc. was founded in 1849 and is headquartered in New York, New York. Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sell biopharmaceutical products worldwide. In December, 2022 announced the U.S. Food and Drug Administration (FDA) granted Emergency Use Authorization (EUA) of their Omicron BA.4/BA.5-adapted bivalent COVID-19 vaccine as the third 3-µg dose in the three-dose primary series for children 6 months through 4 years of age.
4. GlaxoSmithKline PLC
GSK plc, together with its subsidiaries, engages in the creation, discovery, development, manufacture, and marketing of pharmaceutical products, vaccines, over-the-counter medicines, and health-related consumer products in the United Kingdom, the United States, and internationally. It operates through four segments: Pharmaceuticals, Pharmaceuticals R&D, Vaccines, and Consumer Healthcare. GSK plc was founded in 1715 and is headquartered in Brentford, the United Kingdom. On May 2020, it was reported that GSK tap experimental arthritis antibody to calm cytokine storm hitting COVID-19 patients.
5. Cipla Limited
Cipla Limited, together with its subsidiaries, manufactures and sells pharmaceutical products in India, the United States, South Africa, and internationally. The company was incorporated in 1935 and is headquartered in Mumbai, India. Cipla Limited has a licensing agreement with Merck & Co., Inc. for the manufacturing and distribution of Molnupiravir, an investigational oral antiviral drug; a license agreement with Eli Lilly and Company for the manufacture and commercialization of the drug baricitinib for Covid-19 indication; and collaborations with Dr. Reddy's Laboratories Ltd, Sun Pharmaceutical Industries Limited, Emcure Pharmaceuticals Limited, and Torrent Pharmaceuticals Limited for the clinical trial of the investigational oral anti-viral drug Molnupiravir.
6. Novartis AG.
The company was incorporated in 1996 and is headquartered in Basel, Switzerland. Novartis AG researches, develops, manufactures, and markets healthcare products worldwide. Novartis in December, 2022 announced the European Commission (EC) approved Pluvicto® (INN: lutetium (177Lu) vipivotide tetraxetan), a targeted radioligand therapy
7. Bayer AG
Bayer Aktiengesellschaft, together its subsidiaries, operates as a life science company worldwide. It operates through Pharmaceuticals, Consumer Health, and Crop Science segments. Bayer Aktiengesellschaft was founded in 1863 and is headquartered in Leverkusen, Germany.
8. Ipca Laboratories Ltd.
Ipca Laboratories Limited manufactures and markets pharmaceutical formulations and active pharmaceutical ingredients (APIs) for various therapeutic segments in India. The company was incorporated in 1949 and is based in Mumbai, India.
*Definition - Regulatory officials encourage tourists to carry antimalarial medications with them in order to avoid the growing patient pool and lower the risk of contracting malaria while travelling.